What is neoBona?
neoBona is a state-of-the-art non-invasive prenatal genetic screening test. It detects the most frequent chromosomal abnormalities in pregnancy: Down syndrome (trisomy 21), Edwards syndrome (trisomy 18) and Patau syndrome (trisomy 13) together with, optionally, numerical anomalies of the sex (X and Y) chromosomes.
Is this test suitable for me?
neoBona:
- Is performed from a single tube of blood
- Can be performed from 10 weeks of pregnancy (10 weeks + 0 days of amenorrhea)
- Can be performed in cases of assisted reproduction, including IVF after gamete (sperm or egg) donation
- Has been shown by SYNLAB to be accurate also for twin pregnancies
- Is performed only in ISO 15189-accredited expert centres in the European Union
- Is a genetic screening test and, as such, must be prescribed by your physician
Why choose neoBona?
AVAILABLE OPTIONS
neoBona is a state-of-the-art NIPT test that provides highly reliable results for the screening of:
- Most common chromosomal aneuploidies1 (trisomies 21, 18 and 13)
- Sex chromosome abnormalities and fetal sex (where permitted)
neoBona GenomeWide provides the most complete view of the fetal genome analysing all 23 pairs of chromosomes to expand screening to other rare chromosomal2 abnormalities by assessing the presence of:
- Rare autosomal aneuploidies (chromosomes other than 21,18,13 and X and Y)
- Structural anomalies3(large or small deletions or duplications greater than or equal to 7 Mb, on all the autosomes)
1 Alteration in the number of copies of a chromosome.
2 These anomalies could be of clinical relevance as they are associated with miscarriages, various structural alterations, fetal anomalies and developmental and/or growth delays of the fetus.
3 Partial losses or gains of chromosomal regions.
SINGLE PREGNANCY
- Trisomies 21, 18 and 13
- Fetal sex (optional, where permitted)
- Sex chromosome aneuploidies + fetal sex (optional)
TWIN PREGNANCIES
- Trisomies 21, 18 and 13
- Determination of the presence of Y chromosome (optional)
RESULTS
MAXIMUM 5 WORKING DAYS
SINGLE PREGNANCY
- Trisomies 21, 18 and 13
- Fetal sex (optional, where permitted)
- Sex chromosome aneuploidies + fetal sex
- On all autosomal chromosomes (non-sex chromosomes):
- Aneuploidies
- Duplications/deletions (CNVs) greater than or equal to 7 Mb in size
TWIN PREGNANCIES
- Trisomies 21, 18 and 13
- Determination of the presence of Y chromosome
- On all autosomal chromosomes (non-sex chromosomes):
- Aneuploidies
- Duplications/deletions (CNVs) greater than or equal to 7 Mb in size
RESULTS
MAXIMUM 5 WORKING DAYS
For all types of pregnancies: one/two fetuses, IVF, donation, vanishing or non-evolving foetus.